multi N/C® pharma

multi N/C<sup>&reg;</sup> pharma HT & AS variomore pictures

Description

multi N/C® pharma — designed for pharmaceutical use

multi N/C® pharma is uniquely suited for ultrapure water analyses, in particular for the analysis of WFI (Water for Injection), AP (purified water) and liquid and solid samples (swabs) from the cleaning validation.

multi N/C® pharma has been specifically developed for these applications and is available in two models:

  • multi N/C® pharma HT: catalytic high temperature combustion up to 950 °C
  • multi N/C® pharma UV: wet chemical oxidation in High Power UV reactor

Both devices focus on precision and correctness of measuring results in the lower measuring range. This is made possible by the VITA® Flow Management System, by high-volume sample injections with the aid of a high-precision metering valve and the volume-dependent calibration method which allows reliable calibration to the lower ppb range.
Minimum system blank values are achieved by automatic draining of used chemicals. In addition, digestion without blank values is available without reagents.

Highlights multi N/C® pharma

  • Wet chemical oxidation with High Power, Long Life UV reactor with 3 years warranty
  • Thermo-catalytic oxidation at up to 950°C with proven furnace technology with 10 year warranty
  • Maximum sensitivity, precision in ppb range
  • Effective elimination of blank value influences
  • Self Check System (SCS)
  • FDA 21 CRF part 11 compliant
  • SST sequence integrated  in multiWin software
  • Comprehensive qualification certificates (IQ, OQ, PQ)

Features multi NC

Software

multiWin®

The self-explanatory multiWin® software accompanies the user through all relevant menu points. The software monitors and regulates at the same time all the important system parameters and informs immediately about errors in the system configuration and about the input of inappropriate parameters, thus preventing any unusable results from the outset.

multiWin® checks for you the system performance and the quality of the analysis, delivers a clear display of the measurement results, and much more. multiWin® provides free evaluation of sample data even during running measurements, the automatic selection of the optimum calculation function, the fully automatic set up of calibration curves for the various measuring ranges as well as the possibility of individual recalculation of results.

  • Comprehensive user-oriented functions like multi-point calibration, blank value correction, recalculation of results, free choice of results dimensions, statistical functions
  • Automatic or manual data export (LIMS, MS Excel)
  • Comfortable management and storage of data and parameters
  • User management, audit trail and electonic signatures according to FDA 21 CFR part 11
  • Available as PC or as stand alone software version for operation via touch screen

Accessories

AS 10 — autosampler for 10 samples á 50 mL

AS 21 — autosampler for 21 samples á 50 mL

AS vario — variable sample racks with up to 146 sample positions including magnetic stir bars

EPA sampler with “piercing function” — for sampling from septum-capped vials

Swab test module — for the direct combustion of Swabs from the cleaning validation (only for pharma HT)

CLD module — chemiluminescence detector for the measurement of all organic and inorganic nitrogen compounds (only for pharma HT)

Go to multi N/C® series accessories

Applications

Pharmaceutical Industry

 Application Note Total Protein Determination in Pharmaceutical Products (Vaccines) by TNb Analysis

Application Note TOC System Suitability Test According to New USP Regulations

 

 

Application Notes

  • SP_TOC_01_07_e
    .pdf | 356.29 kB

    The TOC Parameter for Cleaning Validation in the Pharmaceutical Industry

  • SP_TOC_02_06_e
    .pdf | 258.41 kB

    TOC Determination in Solid Samples for Cleaning Validation

  • SP_TOC_05_05_e
    .pdf | 158.74 kB

    System Suitability Test

Downloads

Videos

multi N/C® animation

multi N/C® — As Easy As It Gets! Easy use and safe, trouble-free and unattended sample analysis — these are more than ever requirements for a TOC/TNb analyzer. Operation of the instrument even without special knowledge or experience is no problem with a multi N/C®!

Tutorial multi N/C® series FR-NDIR Detector

The core element of the multi N/C® series models is the new Focus Radiation NDIR Detector® equipped with high-quality optics for precise detection of CO2. Energy-rich radiation is focused onto the microdetector with the help of integrated optics. The radiation density obtained in this way surpasses classical detectors many times. This results in higher sensitivity and precision over a wider measurement range.